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No one with high blood pressure, heart disease, diabetes, glaucoma, or a history of stroke should use this herb. Lentinan has been shown to reduce both blood pressure and cholesterol, suggesting usefulness in preventing and treating heart disease and stroke. Anyone with insomnia, anxiety problems, high cholesterol, high blood pressure, diabetes, or heart disease should limit caffeine consumption. Ginseng should be used with discretion if suffering from heart disease and high blood pressure.

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Additionally, with CoQ10, I can run out of it for a day or so and the brainfog doesn't seem to return for several days. Additionally, when my thyroid gland enlarged for a couple of months, I had a normal thyroid scan.